The experiment will combine simultaneous MEG and intracranial local field potential recordings in deep brain stimulation patients to investigate the involvement of different basal ganglia-cortical loops in different symptoms in Parkinson’s disease. (Funded by Parkinson’s Disease Society Clinical Training Fellowship (Dr A. Jha))

 Further reading:

 Litvak V, Eusebio A, Jha A, Oostenveld R, Barnes GR, Penny WD, Zrinzo L, Hariz MI, Limousin P, Friston KJ, Brown P (2010) Optimized beamforming for simultaneous MEG and intracranial local field potential recordings in deep brain stimulation patients. Neuroimage 50(4):1578-88.

 Gaynor LM, Kühn AA, Dileone M, Litvak V, Eusebio A, Pogosyan A, Androulidakis AG, Tisch S, Limousin P, Insola A, Mazzone P, Di Lazzaro V, Brown P (2008) Suppression of beta oscillations in the subthalamic nucleus following cortical stimulation in humans. Eur J Neurosci. 28(8):1686-95.